From heroin and cocaine to weed and alcohol, most of the drugs we know are ultimately made from plants.
But this is changing. A new wave of synthetic drugs entirely made in labs are displacing our familiar narcotics - and transforming the entire future of the drugs world.
These are often new deadly and unstable chemicals like fentanyl and Bath Salts, which are already devastating poor communities.
We look at the biggest macro trend in the future of drugs.
Watch more from this series:
How Queer Clubs Changed the Way We Take Drugs
How Steroids Became More Popular Than Heroin
Why Addiction Theories May Be Wrong
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