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Dr Jasper Brugts (Thoraxcenter, NL) joins us to outline the findings and summarise the take-home messages from the MONITOR-HF trial.

MONITOR-HF was an open-label, randomised trial, done in 25 centres in the Netherlands. Eligible patients had chronic heart failure of New York Heart Association class III and a previous heart failure hospitalisation, irrespective of ejection fraction. Patients were randomly assigned (1:1) to haemodynamic monitoring (CardioMEMS-HF system, Abbott Laboratories) or standard care. Findings presented at Heart Failure 2023 showed PA-guided therapy in addition to SoC with contemporary GDMT resulted in a significant improvement in quality of life and substantial reduction in total HFHs.

Interview Questions:
1. What is the importance of MONITOR-HF?
2. Can you tell us about the CardioMEMS system?
3. What is the study design, patient population and outcomes measures?
4. What are the finding presented at HFA 23?
5. How did MONITOR-HF compare to trials such as CHAMPION and GUIDE-HF?
6. What are the implications for the use of diuretics in GDMT therapy?
7. What are the next steps?

Recorded on-site at HFA 2023, Prague.

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