The AHA COVID-19 Cardiovascular Disease (CVD) Registry captures data on adult patients hospitalized with COVID-19 in over more than 150 hospitals across the US. Radcliffe meets with Dr James de Lemos (UT Southwestern Medical Center, TX, US), co-chair of the registry steering committee, to discuss the important role this registry plays in tackling the pandemic and understanding the complexities of CV complications associated with COVID-19. Questions: What is the background to this registry? What data are you tracking and how many patients have you registered? How did this registry come together and can this be a reference for future registries? What are your findings to date? What are the take-home messages? Recorded remotely from Dallas, 2020. Interviewer: Mirjam Boros Videographer: Natascha Wienand