
Zeba made her television debut with a Pakistan Television drama, Anarkali in 1988. Her melancholic romantic role in Anarkali was widely appreciated. Then, she signed a Bollywood movie Henna in 1991 under the direction of Randhir Kapoor. Henna made Zeba a household name in the subcontinent. Later, she worked in more Bollywood movies like Mohabbat Ki Arzoo (1994), Stuntman (1994), Jai Vikraanta (1995), and Muqadama (1996). But her career in Bollywood didn't make any progress after Henna. Then she came back to Pakistan and worked in Syed Noor directed film Sargam (1995). Her other Lollywood movies include Chief Sahib (1996), Qaid (1996), and Musalman (2001). She produced and directed movie Babu in 2001, and produced a movie Mission 021 in 2014.
Apart from big screen, Zeba also appeared in some popular TV dramas like Tansan, Laag, and Pehli see mohabbat.