The lyrics of "I Miss You Once Again" express a deep sense of longing and heartache. The imagery used is dark and haunting, describing feelings of loneliness and regret. The repetition of "I miss you once again" underscores the intensity of the emotion, while the references to nightmares, shadows, and a "voice inside my head" illustrate the pervasive and inescapable nature of the pain. The lyrics also depict a romanticized yet melancholic view of a past relationship, with mentions of "Jack and Sally" from The Nightmare Before Christmas, suggesting a love that is both eternal and tragically flawed.