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Perry's former personal assistant, two doctors and an alleged drug dealer nicknamed the "Ketamine Queen" are among those arrested.
Perry was found dead in his hot tub at his home in LA on October 28 last year. His autopsy, released in December, found he died from the effects of ketamine.
The five people are all accused of providing Perry with the drug, which was found in his blood at levels in the range used for general anaesthetic in surgery.
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