How does your body clock work? - with Aarti Jagannath

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Find out how the body maintains its circadian clock, and what happens when that clock goes wrong.

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This lecture was filmed at the Ri on 7 April 2025.

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We live in a highly rhythmic environment where the day is a completely different environment from the night, so all life is set to a 24h rhythm, which is governed by a circadian clock within all our cells. Aarti Jagannath will discuss what this clock is, and how it maintains a rhythm, and also how the circadian clock picks up time cues from both the environment and our behaviours to align our internal time with the outside world. Find out what happens when the body clock receives confusing time cues, as it so often does during our 24/7 lifestyles, and what we can do to fix a clock that has gone awry.

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Aarti Jagannath is an Associate Professor at the Nuffield Department of Clinical Neurosciences, University of Oxford. Having read for a DPhil on the mechanisms of RNA interference at Brasenose college, Oxford, she subsequently joined the Sleep and Circadian Neuroscience Institute as a Roche Post-Doctoral Fellow to work on the circadian clock and has stayed in the unit to become a group leader. Aarti was awarded the L’Oreal Women in Science Fellowship in 2015, and the BBSRC David Phillips Fellowship in 2017. She is the founder of a spin-out company, Circadian Therapeutics, that translates some of her group's research into the clinical arena. She is also a mother of two and am a passionate advocate for women in STEM careers.
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