
A westbound ship en route to Apia, Samoa, is temporarily stranded at nearby Pago Pago due to a possible cholera outbreak on board. Among the passengers are Alfred Davidson, a self-righteous missionary, his wife, and Sadie Thompson, a prostitute. Thompson passes the time partying and drinking with the American Marines stationed on the island. Sergeant Tim O'Hara, nicknamed by Sadie as "Handsome", falls in love with her.