JIM 2020: The TAVR Odyssey — Prof Martin B Leon

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Prof Martin B Leon (Columbia University Medical Center, US), a pioneer in the development of minimally invasive therapies for patients with heart disease, discusses transcatheter aortic valve replacement therapy (TAVR) for patients with aortic stenosis.

Prof Leon was honoured with the Lifetime Achievement Award by the American College of Cardiology (ACC) in 2019 for his work.

Questions:

1. What are the origins of TAVR and why was it needed in the first place?
2. Can you remember your first TAVR case? Can you describe how this was performed compared to modern TAVR?
3. What are the most important innovations in TAVR that have made it evolve from a niche therapy to standard-of-care?
4. What were the most important trials to provide validation data?
5. Should TAVR be the default treatment for patients with symptomatic aortic stenosis over surgery now?


Filmed on location at the JIM 2020.

Interviewer: Ashlynne Merrifield
Videographer: Dom Woodruff