
Causes:
• Hematogenous spread: Infection travels to the bone via the bloodstream, often seen in children.
• Contiguous spread: Infection spreads from nearby tissues or wounds, common in adults with foot ulcers or surgical wounds.
• Direct introduction: From an open fracture, surgery, or penetrating injury.
Common Culprits:
• Bacteria: Staphylococcus aureus is the most common.
• Fungi: Rare, seen in immunocompromised individuals.
Risk Factors:
• Diabetes
• Peripheral vascular disease
• Trauma or recent surgery
• Immunosuppression
• Chronic wounds or pressure ulcers
Symptoms:
• Bone pain and tenderness
• Swelling, redness, and warmth over the infected area
• Fever and chills
• Drainage from a wound or sinus tract
• Fatigue or malaise
Diagnosis:
• Imaging: X-rays, MRI, or CT scans to detect bone changes.
• Blood tests: Elevated white blood cell count, ESR, and CRP.
• Biopsy or culture: To identify the causative organism.
Treatment:
• Antibiotics: Often IV initially, followed by oral therapy, depending on severity.
• Surgical intervention: To drain abscesses, remove infected tissue, or stabilize the bone.
• Chronic cases: May require prolonged antibiotics or bone grafting.
Early detection and treatment are crucial to prevent complications, such as bone destruction, abscess formation, or systemic spread of the infection.