
Plot
In 1973, a research team in the Amazon rainforest in Peru led by a pregnant Constance Webb, discovers an unidentified spider species with rare healing properties. Ezekiel Sims, the man Constance hired for protection and security, betrays the team and claims the spider for himself, shooting her in a struggle before fleeing with the spider and leaving Constance to die. An indigenous tribe attempts to save Constance by having one of the spiders bite her. However, she dies shortly after giving birth to her daughter, Cassandra.
30 years later, in 2003, Cassandra, now going by "Cassie", works as a paramedic in New York City alongside her co-workers Ben Parker and O'Neil. During a dangerous call, she falls into the water and has a near-death experience. Ben revives Cassie, but she begins to experience visions. Initially, she dismisses them as déjà vu, but after failing to prevent O'Neil's death, Cassie realizes she can see into the future. Ezekiel, who has limited precognition power and enhanced physical abilities, collects information on 3 teenage girls: Julia Cornwall, Anya Corazón, and Mattie Franklin. His visions lead him to believe that they are destined to kill him. Cassie is also drawn to the girls and intervenes to stop Ezekiel from ambushing them at Grand Central Terminal. She steals a taxi and takes the girls out of the city to hide them in a nearby forest.