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We are joined onsite by principal investigator Dr Rachel Lampert (Yale School of Medicine, US), Dr Sharlene Day (Penn Medicine, US) and Dr Michael Ackerman (Mayo Clinic, US) to discuss the late-breaking findings from the LIVE-HCM Study. In this trial, investigators aimed to determine the effects of lifestyle and exercise on the well-being of patients with hypertrophic cardiomyopathy (HCM) and long-QT syndrome (LQTS). Over 4200 participants were enrolled in the study.

Results showed no increased risk in patients doing vigorous exercise compared to those who were less active.

Interview questions:
1. What is the importance of the LIVE HCM trial?
2. Can you tell us about the study design and methods?
3. Can you please summarise the baseline characteristics of the patients?
4. What data did you present at ACC?
5. How should this data impact patient care and guidelines?
6. What are the next steps?

For more content from ACC.23/WCC and the Late-breaker Discussion series head to Late-Breaking Science Video Collection.


Recorded on site at ACC 2023, New Orleans.

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