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Prof Jan Belohlavek (Charles University of Prague, Prague, CZ) discusses the findings of the Hyperinvasive Approach In Refractory Out-of-hospital Cardiac Arrest: An Open-label Randomized Controlled Trial.

Prague out-of Hospital Cardiac Arrest (OHCA) study compared the use of prehospital intraarrest hypothermia, mechanical chest compression device, extracorporeal life support (ECLS) and early invasive investigation and treatment (coronary angiography/percutaneous coronary intervention [PCI]; pulmonary angiography/percutaneous embolectomy; aortography) in all patients with OHCA of presumed cardiac origin compared to standard of care.

Questions
1. What prompted you to conduct this study?
2. What is the Prague OHCA Study?
3. What was the study design, patient population and endpoints?
4. What are your findings?
5. What conclusions can be made? How should this influence guidelines?
6. What are the next steps?
+ What are take-home messages from this study?

Recorded remotely from Prague, 2021.

Interviewer: Mirjam Boros

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